5-methyl-2-pyridinecarboxylic acid methyl ester

5-methyl-2-pyridinecarboxylic acid methyl ester - Names and Identifiers

Name	methyl 5-methylpyridine-2-carboxylate
Synonyms	NSC 109152 methyl 5-methylpicolinate 5-Methylpicolinic acid methyl ester methyl 5-methylpyridine-2-carboxylate Methyl 5-methylpyridine-2-carboxylate Methyl 5-methyl-2-pyridinecarboxylate 5-Methylpyridine-2-carboxylic acid methyl ester 5-methyl-2-pyridinecarboxylic acid methyl ester 2-pyridinecarboxylic acid, 5-methyl-, methyl ester 2-Pyridinecarboxylic acid, 5-Methyl-, Methyl ester
CAS	29681-38-7
InChI	InChI=1/C8H9NO2/c1-6-3-4-7(9-5-6)8(10)11-2/h3-5H,1-2H3

5-methyl-2-pyridinecarboxylic acid methyl ester - Physico-chemical Properties

Molecular Formula	C8H9NO2
Molar Mass	151.16
Density	1.104
Melting Point	54-55℃
Boling Point	253℃
Flash Point	107℃
Vapor Presure	0.0182mmHg at 25°C
pKa	1.98±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.51

5-methyl-2-pyridinecarboxylic acid methyl ester - Introduction

methyl is an organic compound with the chemical formula C8H9NO2. The following is a description of its nature, use, preparation and safety information:

Nature:
1. Appearance: methyl is a colorless to yellowish liquid.
2. Solubility: soluble in most organic solvents, such as ethanol, ether and dichloromethane.
3. Melting Point: About -5 ℃.
4. Boiling point: About 213~215 ℃.

Use:
1. methyl L is widely used in organic synthesis and can be used as intermediates, catalysts and reagents.
2. It can be used to synthesize other compounds, such as drugs, pesticides, medicines and dyes.

Method:
The preparation method of methyl L is usually obtained by reacting 5-methyl pyridine with methyl formate. The specific preparation method is as follows:
5-methyl pyridine and methyl formate are reacted under appropriate reaction conditions, and excess methyl formate is commonly used as the reaction solvent. After the reaction has been carried out for some time, the target product is extracted by distillation.

Safety Information:
1. methyl L is irritating, avoid direct contact with skin and eyes. Wear appropriate protective gloves and goggles when using.
2. Avoid inhalation of its vapor, such as toxic substances or harmful gas release, please quickly evacuate the site.
3. Storage should be sealed, away from the fire and flammable materials.

Last Update：2024-04-09 02:00:45